Halonium-Induced Polyene Cyclizations
نویسندگان
چکیده
منابع مشابه
New samarium diiodide-induced cyclizations*
Samarium diiodide (SmI2) smoothly promotes the cyclizations of suitably substituted carbonyl compounds with styrene subunits leading to benzannulated cyclooctenes. The intramolecular samarium ketyl addition to arene or hetarene moieties enables a new, efficient, and highly stereoselective entry to dearomatized products such as hexahydronaphthalenes, steroid-like tetraor pentacyclic compounds, o...
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The halonium metathesis reaction of ketones and aldehydes, C=O + XF+ → C=F+ + X=O is difficult to harness for three reasons: (1) the interchange of F+ for O is so exothermic that the C=F+ product ion often decomposes further; (2) the adduct of XF+ to the carbonyl oxygen frequently undergoes side reactions to the virtual exclusion of metathesis; and (3) the metathesis ion is liable to rearrange ...
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A series of γ-oxo esters suitably substituted with various styrene subunits was subjected to samarium diiodide-induced 8-endo-trig cyclizations. Efficacy, regioselectivity and stereoselectivity of these reactions via samarium ketyls strongly depend on the substitution pattern of the attacked alkene moiety. The stereoselectivity of the protonation of the intermediate samariumorganyl is also infl...
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Substituted 1,4-phenanthrenequinones such as 1 are useful building blocks for the preparation of novel materials. Katz and others have shown that compounds such as 1 can be transformed into helicenes by DielsAlder reactions.1 Certain 1,4-phenanthrenequinones also have potential as synthetic intermediates for natural products synthesis. Additionally, some naturally occurring 1,4-phenanthrenequin...
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ZYGMUNT, WALTER A. (Mead Johnson Research Center, Evansville, Ind.). Intracellular loss of potassium in Candida albicans after exposure to polyene antifungal antibiotics. Appl. Microbiol. 14:953-956. 1966.-Eleven antifungal antibiotics, representing three broad macrolide classes, were studied in Candida albicans for their effect on growth and on the fate of intracellular K+. Marked differences ...
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ژورنال
عنوان ژورنال: Synthesis
سال: 2019
ISSN: 0039-7881,1437-210X
DOI: 10.1055/s-0037-1612254